Enbrel
Trovati 15 articoli
- Etanercept associated with tuberculosis and infections
- Amgen and Wyeth Pharmaceuticals have added a Boxed Warning to the Enbrel ( Etanercept ) US Prescribing Information to further strengthen and clarify information regarding the risk of infections, including tuberculosis in patients taking Enbrel; namely the new recommendation to screen for latent t... (Leggi Articolo)
- TNF-alpha antagonists associated with serious skin reactions
- Safety reviews of tumor necrosis factor-alpha ( TNF-a ) antagonists, Infliximab ( Remicade ), Etanercept ( Enbrel ), and Adalimumab ( Humira ) identified rare cases of serious skin reactions, including erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis, associated with ... (Leggi Articolo)
- TNF-alpha inhibition linked to invasive fungal infections
- Tumor necrosis factor a ( TNF- alpha ) blockade has emerged as a useful therapy for collagen vascular diseases or graft-vs-host disease. Fungal infections complicating such therapy have been reported sporadically. Of the 281 cases of invasive fungal infections associated with TNF-alpha inhibit... (Leggi Articolo)
- Diabetes: promising advances in islet cell transplants
- Researchers at University of Illinois at Chicago ( UIC ) have modified the procedure for islet cell transplantation and achieved insulin independence in diabetes patients with fewer but better-functioning pancreatic islet cells. The study results are published in the American Journal of Transp... (Leggi Articolo)
- Autoimmune disease: cardiovascular benefits of anti-TNF therapy in rheumatoid arthritis
- A chronic autoimmune disease, rheumatoid arthritis is characterized by persistent inflammation of the synovial membrane and progressive joint destruction. Beyond loss of mobility, sufferers face a high risk of heart failure. An inflammatory cytokine known for contributing to the development of ... (Leggi Articolo)
- Several serious reactions linked to TNF-alpha inhibitors
- Tumour necrosis factor alpha ( TNF-alpha ) is a cellular protein produced by the immune system and is an important mediator of many diseases, including inflammatory arthritis and inflammatory bowel disease. Currently, three tumour necrosis factor alpha blocking agents are registered in Australi... (Leggi Articolo)
- Spondylarthritis: the process of ankylosis could become a separate therapeutic target
- Any form of arthritis that affects one or more vertebral joints, spondylarthritis ( SpA ) represents a group of closely related disorders, including ankylosing spondylitis ( AS ), psoriatic arthritis ( PsA ), and arthritis associated with inflammatory bowel disease. Aside from chronic inflamma... (Leggi Articolo)
- Bone marrow transplant: TNF level predicts who will develop deadly complication
- Researchers could determine one week after a bone marrow transplant which patients were likely to develop a serious and deadly complication, making them candidates for preventive treatment before any symptoms occur. Researchers at the University of Michigan Comprehensive Cancer Center measure... (Leggi Articolo)
- New indication for Enbrel: psoriatic arthritis
- FDA ( Food and Drug Administration ) approved an expanded indication for Enbrel ( Etanercept ) to improve physical function in patients with psoriatic arthritis. In addition, the FDA approved an update to the Enbrel label to include new radiographic data demonstrating that the drug continued t... (Leggi Articolo)
- Rheumatoid arthritis, TNF-alpha blockers may cause skin diseases
- A prospective cohort study found that Tumour Necrosis Factor alpha ( TNF-alpha ) blocking agents, trigger skin conditions in 25% of patients with rheumatoid arthtitis. TNF-alpha blocking agents has had a remarkable effect on disease activity in a number of rheumatic diseases, including rheumat... (Leggi Articolo)
- Humira plus Methotrexate effective for long standing rheumatoid arthritis
- Combined treatment with Adalimumab ( Humira ) and Methotrexate is about five times more effective than Methotrexate alone in people with long-standing rheumatoid arthritis. In six randomized controlled trials, comprising 2381 people with at least 10 years of the disease, the authors report tha... (Leggi Articolo)
- Autoantibody formation in patients with rheumatoid arthritis treated with Infliximab
- Long-term use of anti-TNF-alpha agents can lead to the development of autoantibodies. Infliximab ( Remicade ) is a chimeric human-murine monoclonal antibody that inhibits TNF-alpha. Investigators from the Department of Rheumatology, University Hospital, Umea ( Sweden ) studied the prevalen... (Leggi Articolo)
- TNF alpha as a novel therapeutic target in symptomatic corticosteroid-dependent asthma
- Researchers have uncovered a potentially new treatment approach for severe asthma, by blocking a powerful immune system chemical, present in large amounts in patients with the severe form of the disease. The study is published in Thorax. Around one in 10 asthmatics has the severe form of th... (Leggi Articolo)
- Rheumatoid arthritis: Etanercept and Methotrexate combination has demonstrated improvement in physical function and kept joint damage from progressing
- Data from a long-term blinded study of anti-TNF agent in patients with rheumatoid arthritis demonstrated that more than three quarters of patients treated with Enbrel ( Etanercept ) plus Methotrexate combination therapy experienced no progression of joint damage at three years. These new resul... (Leggi Articolo)
- TNF blockers linked to lymphoma risk
- The manufacturers of the drugs Humira ( Adalimumab ), Remicade ( Infliximab ) and Enbrel ( Etanercept ) have added new safety information to the labels for these products about malignancies. These three drugs are tumor necrosis factor ( TNF ) blocking agents, and they're used to treat rheumatoi... (Leggi Articolo)
