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Reports of progressive multifocal leukoencephalopathy in CellCept treated patients
In agreement with the EMEA ( European Medicines Agency ), F.Hoffmann-La Roche has informed HealthCare Professional of new safety information regarding CellCept ( Mycophenolate mofetil ). Isolated cases of progressive multifocal leukoencephalopathy ( PML ) have been reported in patients receivi... (Leggi Articolo) anno: 2008| Raking: 0.22222222222222
Cases of progressive multifocal leukoencephalopathy in patients receiving Mycophenolate mofetil
In agreement with the EMEA, F.Hoffmann-La Roche informed Health Care Professionals of new safety information regarding CellCept ( Mycophenolate mofetil ). • Isolated cases of progressive multifocal leukoencephalopathy ( PML ) have been reported in patients receiving CellCept . The case report... (Leggi Articolo) anno: 2008| Raking: 0.2
Autoimmune disease: cardiovascular benefits of anti-TNF therapy in rheumatoid arthritis
A chronic autoimmune disease, rheumatoid arthritis is characterized by persistent inflammation of the synovial membrane and progressive joint destruction. Beyond loss of mobility, sufferers face a high risk of heart failure. An inflammatory cytokine known for contributing to the development of ... (Leggi Articolo) anno: 2008| Raking: 0.1
Erectile dysfunction drugs linked to potential risk of sudden hearing loss
The FDA ( Food and Drug Administration ) has approved labeling changes for erectile dysfunction drugs in the class that includes Cialis ( Tadalafil ), Levitra ( Vardenafil ), and Viagra ( Sildenafil ), to display more prominently the potential risk of sudden hearing loss. In addition, the FDA ... (Leggi Articolo) anno: 2007| Raking: 0.18181818181818
Potentially life threatening side effects combining Tekturna with Diovan
Combining Aliskiren ( Rasilez / Tekturna ) with Valsartan ( Diovan / Tareg ) at maximum recommended doses provides significantly greater reductions in blood pressure than does monotherapy with either agent alone in patients with hypertension. However, an accompanying comment author has raised c... (Leggi Articolo) anno: 2007| Raking: 0.11111111111111
Revised guidelines for unstable angina and non-ST-elevation myocardial infarction
The American College of Cardiology ( ACC ) and the American Heart Association ( AHA ) have jointly released revised Guidelines for the Management of Patients with Unstable Angina and Non-ST-Elevation Myocardial Infarction. Major changes to the guidelines include: suggesting an initial non-invas... (Leggi Articolo) anno: 2007| Raking: 0.11111111111111
Australia: urgent advice regarding management of patients taking Lumiracoxib
As of 10 August 2007, the TGA ( Therapeutic Goods Administration ) had received eight reports of serious liver adverse reactions associated with use of Lumiracoxib ( Prexige ), including two deaths and two patients requiring liver transplants. All these reports have been received since March 2007... (Leggi Articolo) anno: 2007| Raking: 0.11111111111111
Serious liver adverse reactions associated with use of Prexige
As of 10 August 2007, the TGA ( Therapeutic Goods Administration ), in Australia, had received eight reports of serious liver adverse reactions associated with use of Lumiracoxib ( Prexige ), including two deaths and two patients requiring liver transplants. All these reports have been received... (Leggi Articolo) anno: 2007| Raking: 0.11111111111111
Treatment of erectile dysfunction linked to non-arteritic anterior ischaemic optic neuropathy
Viagra ( Sildenafil ) and Cialis ( Tadalafil ), the drugs used to treat impotency, may be associated with an increased risk of optic nerve damage in men with a history of heart attack or high blood pressure. The study is published in the British Journal of Ophthalmology. Healthcare profess... (Leggi Articolo) anno: 2006| Raking: 0.45454545454545
Vaginal oestrogen linked to mammary carcinoma
Breast tumor specialists cautioned doctors of the risks in prescribing vaginal oestrogen to breast cancer patients being treated with the new aromatase inhibiting drugs, Anastrozole ( Arimidex ), Letrozole ( Femara ) and Exemestane ( Aromasin ). Their concerns follow findings from the first st... (Leggi Articolo) anno: 2006| Raking: 0.33333333333333
How one disease may prevent another
The knowledge that one disease may prevent the onset of another is not new. For example, the discovery that cowpox vaccines can prevent smallpox dates back to 1798. E. Richard Stiehm, at the Mattel Children's Hospital at UCLA, researched examples throughout medical history of ways that one di... (Leggi Articolo) anno: 2006| Raking: 0.16666666666667
Phosphodiesterase-5 inhibitors affect other organ systems
Ernst R Schwarz, at Cedars-Sinai Medical Center, and colleagues concluded a review of the medical literature, as well as their own research findings and clinical data, to determine what actually is known about the effects of long-term use of phosphodiesterase-5 inhibitors ( PDE-5i ), on various o... (Leggi Articolo) anno: 2006| Raking: 0.16666666666667
Two-thirds of patients with REM sleep behavior disorder develop degenerative brain diseases later in life
Researchers at Mayo Clinic have found that almost two-thirds of patients with REM sleep behavior disorder ( RBD ) develop degenerative brain diseases by approximately 11 years after diagnosis of RBD. " This study found REM sleep behavior disorder most frequently led to neurodegenerative diseas... (Leggi Articolo) anno: 2006| Raking: 0.13333333333333
Inhaled Cyclosporine improves survival for lung transplant patients
A study conducted at the University of Pittsburgh and led by lung disease specialists who are now at the University of Maryland in Baltimore has found that an inhaled anti-rejection drug can dramatically improve survival after a lung transplant. The results of the study are published in the Ne... (Leggi Articolo) anno: 2006| Raking: 0.125
Inhaled Cyclosporine improves survival for lung transplant patients
A study conducted at the University of Pittsburgh and led by lung disease specialists who are now at the University of Maryland in Baltimore has found that an inhaled anti-rejection drug can dramatically improve survival after a lung transplant. The results of the study are published in the Ne... (Leggi Articolo) anno: 2006| Raking: 0.125
Inhaled Cyclosporine improves survival for lung transplant patients
A study conducted at the University of Pittsburgh and led by lung disease specialists who are now at the University of Maryland in Baltimore has found that an inhaled anti-rejection drug can dramatically improve survival after a lung transplant. The results of the study are published in the Ne... (Leggi Articolo) anno: 2006| Raking: 0.125
Vitamin A deficiency linked to major intestinal surgery
A small study found that major intestinal surgery, including stomach reduction for obesity, may boost the chances of subsequent vitamin A deficiency. The researchers have based their findings on three patients with increasingly poor eyesight or night blindness, who attended a specialist eye cl... (Leggi Articolo) anno: 2006| Raking: 0.125
Vardenafil may protect the heart following acute myocardial infarction
Researchers at Virginia Commonwealth University ( VCU ) found that Levitra ( Vardenafil ), an erectile dysfunction drug, protects the heart against tissue damage following acute myocardial infarction. " Our findings further support the concept that the novel class of phosphodiesterase-5 inhi... (Leggi Articolo) anno: 2006| Raking: 0.11111111111111
Disulfiram and Carbimide help patients achieve high rates of long-term abstinence
Studies investigating the long-term outcomes of alcoholism treatment are rare and inconsistent. A nine-year study in the Alcoholism: Clinical & Experimental Research investigated the occurrence of abstinence, lapse, and relapse among chronic alcoholics while exploring the role that "alcohol dete... (Leggi Articolo) anno: 2006| Raking: 0.090909090909091
Pharmacogenetics could reduce the incidence of adverse reactions and optimize treatments
Researchers, at Washington University School of Medicine in St. Louis and the St. Louis College of Pharmacy, found that 29 percent of patients seen at local primary-care offices had taken at least one of 16 drugs that can cause adverse reactions in genetically susceptible people. Applying inf... (Leggi Articolo) anno: 2006| Raking: 0.090909090909091
Liver transplant can be successful in HIV patients with hepatitis B
A study on HIV patients who also had hepatitis B virus ( HBV ) found that better outcomes are possible if they are referred early for transplant and treated with a combination of drugs for HBV. It is essential to monitor the HBV status of these patients, however, in order to control the emergen... (Leggi Articolo) anno: 2006| Raking: 0.090909090909091
Pharmacogenetics could reduce the incidence of adverse reactions and optimize treatments
Researchers, at Washington University School of Medicine in St. Louis and the St. Louis College of Pharmacy, found that 29 percent of patients seen at local primary-care offices had taken at least one of 16 drugs that can cause adverse reactions in genetically susceptible people. Applying inf... (Leggi Articolo) anno: 2006| Raking: 0.090909090909091
Pharmacogenetics could reduce the incidence of adverse reactions and optimize treatments
Researchers, at Washington University School of Medicine in St. Louis and the St. Louis College of Pharmacy, found that 29 percent of patients seen at local primary-care offices had taken at least one of 16 drugs that can cause adverse reactions in genetically susceptible people. Applying inf... (Leggi Articolo) anno: 2006| Raking: 0.090909090909091
Mutation in gene for PDE11A associated with development of micronodular adrenocortical hyperplasia
Researchers at the National Institutes of Health ( NHI ) have discovered that a rare tumor of the adrenal glands appears to result from a genetic deficiency of an important enzyme. The enzyme is one of a class of enzymes involved in halting a cell's response to hormones and appears to stop cells ... (Leggi Articolo) anno: 2006| Raking: 0.076923076923077
Erectile dysfunction: irreversible vision loss due phosphodiesterase 5 inhibitors
Public Citizen, representing more than 135,000 U.S. consumers, submitted a petition to the FDA ( Food and Drug Administration ) to immediately add a black box warning regarding the risks of drug-induced blindness for the three phosphodiesterase 5 ( PDE5 ) inhibitors that are prescribed for the tr... (Leggi Articolo) anno: 2005| Raking: 0.5
Impotence drugs: visual loss could be linked to Sildenafil, Tadalafil, Vardenafil
The Food and Drug Administration ( FDA ) has approved new labeling for Cialis ( Tadalafil ), Viagra ( Sildenafil ), and Levitra ( Vardenafil ) regarding postmarketing reports of vision loss related to NAION ( non-arteritic anterior ischemic optic neuropathy ). Most, but not all, of these pat... (Leggi Articolo) anno: 2005| Raking: 0.18181818181818
Post traumatic stress disorder after traumatic events
The National Institute for Clinical Excellence ( NICE ) has issued guidelines for the NHS on how to improve the recognition, screening and treatment of post traumatic stress disorder ( PTSD ) in children and adults in primary and secondary care. PTSD can affect anyone and is common – around ... (Leggi Articolo) anno: 2005| Raking: 0.14285714285714
Public Citizen calls on FDA to withdraw Pemoline
Public Citizen, a US consumer organization, petitioned the Food and Drug Administration ( FDA ) to immediately remove Pemoline ( Cylert ), an Abbott’s CNS stimulant used in the treatment of attention deficit hyperactivity disorder ( ADHD ), from the market because it is known to have caused at le... (Leggi Articolo) anno: 2005| Raking: 0.125
Rheumatoid arthritis, TNF-alpha blockers may cause skin diseases
A prospective cohort study found that Tumour Necrosis Factor alpha ( TNF-alpha ) blocking agents, trigger skin conditions in 25% of patients with rheumatoid arthtitis. TNF-alpha blocking agents has had a remarkable effect on disease activity in a number of rheumatic diseases, including rheumat... (Leggi Articolo) anno: 2005| Raking: 0.125
Hemodialysis: Heparin antibodies linked to more adverse outcomes
Researchers at Mayo Clinic searching for explanations of high mortality rates among kidney failure patients undergoing hemodialysis are focusing their attention on the use of Heparin, a drug used to reduce clotting of the blood. In the study, they found patients who had a higher level of adve... (Leggi Articolo) anno: 2005| Raking: 0.125
FDA approves BiDil in black patients with heart failure
FDA ( Food and Drug Administration ) approved BiDil ( Isosorbide dinitrate/Hydralazine hydrochloride ) for the treatment of heart failure in black patients. BiDil is indicated to improve survival, prolong time to hospitalization for heart failure and improve patient-reported functional status... (Leggi Articolo) anno: 2005| Raking: 0.11111111111111
Risk of cancer after low doses of ionising radiation
The largest study of nuclear industry workers ever conducted found low doses of radiation are associated with a risk of developing cancer. This study brings the largest body of evidence to date concerning the effects of low dose chronic exposure to ionising radiation. Ionising radiation is... (Leggi Articolo) anno: 2005| Raking: 0.11111111111111
Higher risks of sexually-transmitted diseases for recreational use of erectile dysfunction drugs
Recreational use used to treat erectile dysfunction, of drugs -- Sildenafil ( Viagra ), Tadalafil ( Cialis ) and Vardenafil ( Levitra ) -- is associated with higher risks of sexually-transmitted diseases ( STD's ), including HIV. Researchers from the San Francisco Department of Public Healt... (Leggi Articolo) anno: 2005| Raking: 0.083333333333333
Betamethasone given to pregnant women can affect brains and behaviour of their grandchildren
A study in guinea pigs suggests that a drug commonly given to pregnant women to help their babies mature enough to survive can also affect the brains and behaviour of their grandchildren too. The finding raises a difficult dilemma for doctors, for while the drug undoubtedly saves lives, its side... (Leggi Articolo) anno: 2005| Raking: 0.076923076923077